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检索条件"主题词=Lectin Microarray"
107 条 记 录,以下是11-20 订阅
排序:
Survey of glycoantigens in cells from α1-3galactosyltransferase knockout pig using a lectin microarray
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XENOTRANSPLANTATION 2010年 第1期17卷 61-70页
作者: Miyagawa, Shuji Takeishi, Shunsaku Yamamoto, Aki Ikeda, Kosuke Matsunari, Hitomi Yamada, Masao Okabe, Masaru Miyoshi, Eiji Fukuzawa, Masahiro Nagashima, Hiroshi Osaka Univ Grad Sch Med Dept Surg Div Organ Transplantat E9 Suita Osaka 5650871 Japan Moritex Corp Glyc Res Lab Yokohama Kamagra Japan Meiji Univ Dept Life Sci Kawasaki Kamagra Japan Osaka Univ Microbial Dis Res Inst Osaka Japan Osaka Univ Grad Sch Med Dept Mol Biochem & Clin Invest Osaka Japan
Background: Glycoantigens represent major obstacles to successful xenotransplantation. Even after the alpha 1-3galactosyltransferase (GalT) gene knockout (GalT-KO) pigs were produced, non-Gal antigens continue to be p... 详细信息
来源: 评论
Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study
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BMC CANCER 2020年 第1期20卷 192-192页
作者: Takayama, Hiroomi Ohta, Masayuki Iwashita, Yukio Uchida, Hiroki Shitomi, Yuki Yada, Kazuhiro Inomata, Masafumi Oita Univ Fac Med Dept Gastroenterol & Pediat Surg 1-1 IdaigaokaHasama Machi Oita 8795593 Japan Oita Univ Global Oita Med Adv Res Ctr Hlth Oita Japan
BackgroundAltered glycosylation associated with hepatocellular carcinoma (HCC) is well documented. However, few reports have investigated the association between dedifferentiation and glycosylation. Therefore, the aim... 详细信息
来源: 评论
Altered N-Glycan Expression Profile in Epithelial-to-Mesenchymal Transition of NMuMG Cells Revealed by an Integrated Strategy Using Mass Spectrometry and Glycogene and lectin microarray Analysis
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JOURNAL OF PROTEOME RESEARCH 2014年 第6期13卷 2783-2795页
作者: Tan, Zengqi Lu, Wei Li, Xiang Yang, Ganglong Guo, Jia Yu, Hanjie Li, Zheng Guan, Feng Jiangnan Univ Sch Biotechnol Minist Educ Key Lab Carbohydrate Chem & Biotechnol Wuxi 214122 Jiangsu Peoples R China Jiangnan Univ Wuxi Med Sch Wuxi 214122 Jiangsu Peoples R China NW Univ Xian Coll Life Sci Lab Funct Glyc Xian 710069 Peoples R China
Epithelial-to-mesenchymal transition (EMT) is an essential biological process that occurs in embryonic development, metastatic diseases, and cancer progression. Altered expression of glycans is known to be associated ... 详细信息
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Identification of Cell Surface Glycoprotein Markers for Glioblastoma-Derived Stem-Like Cells Using a lectin microarray and LC-MS/MS Approach
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JOURNAL OF PROTEOME RESEARCH 2010年 第5期9卷 2565-2572页
作者: He, Jintang Liu, Yashu Xie, Xiaolei Zhu, Thant Soules, Mary DiMeco, Francesco Vescovi, Angelo L. Fan, Xing Lubman, David M. Univ Michigan Med Ctr Dept Surg Ann Arbor MI 48109 USA Univ Michigan Med Ctr Dept Neurosurg Ann Arbor MI 48109 USA Univ Michigan Med Ctr Dept Cell & Dev Biol Ann Arbor MI 48109 USA Johns Hopkins Univ Baltimore MD 21205 USA Ist Nazl Neurol Carlo Besta Dept Neurosurg I-20133 Milan Italy Univ Milano Bicocca Dept Biosci & Biotechnol I-20126 Milan Italy
Despite progress in the treatment of glioblastoma, more than 95% of patients suffering from this disease still die within 2 years. Recent findings support the belief that cancer stem-like cells are responsible for tum... 详细信息
来源: 评论
A novel strategy for mammalian cell surface glycome profiling using lectin microarray
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GLYCOBIOLOGY 2007年 第10期17卷 1138-1146页
作者: Tateno, Hiroaki Uchiyama, Noboru Kuno, Atsushi Togayachi, Akira Sato, Takashi Narimatsu, Hisashi Hirabayashi, Jun Natl Inst Adv Ind Sci & Technol Res Ctr Med Glycosci Tsukuba 3058568 Japan
The glycome represents the total set of glycans expressed in a cell. The glycome has been assumed to vary between cell types, stages of development and differentiation, and during malignant transformation. Analysis of... 详细信息
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The use of lectin microarray for assessing glycosylation of therapeutic proteins
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MABS 2016年 第3期8卷 524-535页
作者: Zhang, Lei Luo, Shen Zhang, Baolin Food & Drug Adm Ctr Drug Evaluat & Res Off Biotechnol Prod Silver Spring MD USA
Glycans or carbohydrates attached to therapeutic glycoproteins can directly affect product quality, safety and efficacy, and therefore must be adequately analyzed and controlled throughout product life cycles. However... 详细信息
来源: 评论
High-precision multiclass cell classification by supervised machine learning on lectin microarray data
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REGENERATIVE THERAPY 2020年 15卷 195-201页
作者: Shibata, Mayu Okamura, Kohji Yura, Kei Umezawa, Akihiro Natl Ctr Child Hlth & Dev Dept Reprod Biol Tokyo 1578535 Japan Ochanomizu Univ Grad Sch Humanities & Sci Tokyo 1128610 Japan Natl Ctr Child Hlth & Dev Dept Syst BioMed Tokyo 1578535 Japan Waseda Univ Sch Adv Sci & Engn Tokyo 1620041 Japan
Introduction: Establishment of a cell classification platform for evaluation and selection of human pluripotent stem cells (hPSCs) is of great importance to assure the efficacy and safety of cell-based therapy. In our... 详细信息
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Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
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AGING CELL 2020年 第8期19卷 e13190-e13190页
作者: Oinam, Lalhaba Changarathil, Gopakumar Raja, Erna Ngo, Yen Xuan Tateno, Hiroaki Sada, Aiko Yanagisawa, Hiromi Univ Tsukuba Life Sci Ctr Survival Dynam Tsukuba Adv Res Alliance TARA Tsukuba Ibaraki Japan Univ Tsukuba Sch Integrat & Global Majors PhD Program Human Biol Tsukuba Ibaraki Japan Univ Tsukuba Grad Sch Comprehens Human Sci Tsukuba Ibaraki Japan Kumamoto Univ Int Res Ctr Med Sci IRCMS Kumamoto Japan Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Tsukuba Cent 61-1-1 Higashi Tsukuba Ibaraki 3058566 Japan Univ Tsukuba Fac Med Tsukuba Ibaraki Japan
Aging in the epidermis is marked by a gradual decline in barrier function, impaired wound healing, hair loss, and an increased risk of cancer. This could be due to age-related changes in the properties of epidermal st... 详细信息
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Fucosylation is associated with the malignant transformation of intraductal papillary mucinous neoplasms: a lectin microarray-based study
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SURGERY TODAY 2016年 第10期46卷 1217-1223页
作者: Watanabe, Kiminori Ohta, Masayuki Yada, Kazuhiro Komori, Yoko Iwashita, Yukio Kashima, Kenji Inomata, Masafumi Oita Univ Fac Med Dept Gastroenterol & Pediat Surg Hasama Machi Oita 8795593 Japan Oita Prefectural Hosp Dept Pathol Oita Japan
Intraductal papillary mucinous neoplasm (IPMN) is an intraductal mucin-producing pancreatic neoplasm with the potential for malignant transformation. Changes in glycans expressed on the cell surface and glycotransfera... 详细信息
来源: 评论
Combinatorial Approach with Mass Spectrometry and lectin microarray Dissected Site-Specific Glycostem and Glycoleaf Features of the Virion-Derived Spike Protein of Ancestral and γ Variant SARS-CoV-2 Strains
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JOURNAL OF PROTEOME RESEARCH 2024年 第4期23卷 1408-1419页
作者: Hiono, Takahiro Sakaue, Hiroaki Tomioka, Azusa Kaji, Hiroyuki Sasaki, Michihito Orba, Yasuko Sawa, Hirofumi Kuno, Atsushi Natl Inst Adv Ind Sci & Technol Cellular & Mol Biotechnol Res Inst Mol & Cellular Glycoprote Res Grp Tsukuba Ibaraki 3058565 Japan Hokkaido Univ One Hlth Res Ctr Sapporo Hokkaido 0600818 Japan Hokkaido Univ Fac Vet Med Dept Dis Control Lab Microbiol Sapporo Hokkaido 0600818 Japan Hokkaido Univ Int Inst Zoonosis Control Int Collaborat Unit Sapporo Hokkaido 0010020 Japan Hokkaido Univ Inst Vaccine Res & Dev HU IVReD Sapporo Hokkaido 0010021 Japan Hokkaido Univ Int Inst Zoonosis Control Div Mol Pathobiol Sapporo Hokkaido 0010020 Japan
The coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted public health globally. As the glycosylation of viral envelope glycoproteins is strongl... 详细信息
来源: 评论