Objective:This is an intervention study which explores the effect of using virtual reality training system(VRTS)to improve cognitive function deficiency and clinical symptoms in Han Chinese patients with schizophrenia...
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Objective:This is an intervention study which explores the effect of using virtual reality training system(VRTS)to improve cognitive function deficiency and clinical symptoms in Han Chinese patients with schizophrenia in the remission ***68 patients with schizophrenia in the remission stage were recruited for the interventional study and were randomly allocated(1:1 ratio) to either virtual reality training(VRT) group or treatment-as-usual(TAU) *** VRT group,patients received VRT for two weeks and antipsychotic treatment as usual while TAU group only received antipsychotic treatment as *** function and changes of clinical symptoms before and after intervention were assessed by MATRICS Consensus Cognitive Battery(MCCB),Positive and Negative Syndrome Scale(PANSS),and the Personal and Social Performance Scale(PSP).Results:Results showed(1) VRT could improve MCCB composite scores and 4 out of 7 cognitive domains:speed of processing,working memory,visual learning,reasoning and problem solving,and(2) VRT could alleviate general psychopathology symptoms but did not benefit for positive and negative symptoms of PANSS among patients with schizophrenia in the remission stage Conclusions:There is therapeutic effect of VR technology in patients with schizophrenia in the remission *** may improve cognitive function impairment and general psychopathology symptoms.
目的:探讨广泛性焦虑患者焦虑严重程度、焦虑类型与心率变异性频谱指标的相关性研究.方法:对50例符合D S M-V诊断标准的广泛性焦虑患者和50例健康志愿者分为病例组和对照组,完成一般情况和病史问卷,采用汉密尔顿焦虑量表(H A M A)和汉...
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目的:探讨广泛性焦虑患者焦虑严重程度、焦虑类型与心率变异性频谱指标的相关性研究.方法:对50例符合D S M-V诊断标准的广泛性焦虑患者和50例健康志愿者分为病例组和对照组,完成一般情况和病史问卷,采用汉密尔顿焦虑量表(H A M A)和汉密尔顿抑郁量表(HAMD)评定患者焦虑和抑郁状况,排除有抑郁的患者.采用心电工作站记录器记录所有被试的心率变异性指标,频谱分析TP、HFnorm、LFnorm、LF/HF指标,并对广泛性焦虑患者HAMA评分与心率变异性频谱指标进行并相关分析.结果:(1)治疗组和对照组在性别、年龄、受教育年限、婚姻等一般资料比较无统计学差异(P>0.05);(2)三组患者间精神焦虑因子分比较存在显著差异性(P<0.01),躯体焦虑因子分比较存在差异性(P<0.05)有统计学意义;轻度组和中度组躯体焦虑因子和精神焦虑因子分比较存在显著差异(P<0.01),有统计学意义;重度组躯体焦虑和精神焦虑因子分比较差异无统计学意义(P>0.05);H A M A躯体焦虑因子分与L F、L F/H F呈正相关(P<0.05),有统计学意义,与T P、H F相关性极小(P>0.05),无统计学意义;精神焦虑因子分与TP、LF、HF、LF/HF相关性极小(P>0.05),无统计学意义.结论:广泛性焦虑患者静息状态下自主神经功能降低,其焦虑严重程度与HRV频域指标存在一定相关性.
经颅磁刺激(Transcranial Magnetic Stimulation,TMS)是一种利用脉冲磁场作用于中枢神经系统(主要是大脑),改变皮层神经细胞膜电位,使之产生感应电流,影响脑内代谢和神经电活动,从而引起一系列生理生化反应的磁刺激技术.重复经颅磁刺激(...
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经颅磁刺激(Transcranial Magnetic Stimulation,TMS)是一种利用脉冲磁场作用于中枢神经系统(主要是大脑),改变皮层神经细胞膜电位,使之产生感应电流,影响脑内代谢和神经电活动,从而引起一系列生理生化反应的磁刺激技术.重复经颅磁刺激(Reptitive Transcranial Magnetic Stimulation rTMS),是在TMS基础上发展起来的的新的神经电生理技术[1],因具有无创,操作简单,安全性好等特点,目前已被广泛应用于神经精神领域研究或治疗,包括抑郁症、焦虑症,精神分裂症、强迫症等.治疗的各个环节需要人员密切配合,以达到预期的效果,现介绍治疗体会如下.
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