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Enterotypes in the landscape of gut microbial community composition (vol 3, pg 8, 2017)

NATURE MICROBIOLOGY 2018年第3期3卷 388-388页

作者： Costea, Paul I. Hildebrand, Falk Arumugam, Manimozhiyan Backhed, Fredrik Blaser, Martin J. Bushman, Frederic D. de Vos, Willem M. Ehrlich, S. Dusko Fraser, Claire M. Hattori, Masahira Huttenhower, Curtis Jeffery, Ian B. Knights, Dan Lewis, James D. Ley, Ruth E. Ochman, Howard O'Toole, Paul W. Quince, Christopher Relman, David A. Shanahan, Fergus Sunagawa, Shinichi Wang, Jun Weinstock, George M. Wu, Gary D. Zeller, Georg Zhao, Liping Raes, Jeroen Knight, Rob Bork, Peer European Molecular Biology Laboratory Heidelberg Germany. VIB Center for Microbiology VIB Belgium. Laboratory of Microbiology Vrije Universiteit Brussel Brussels Belgium. The Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark. Wallenberg Laboratory Department of Molecular and Clinical Medicine Institute of Medicine Sahlgrenska Academy University of Gothenburg Gothenburg Sweden. Novo Nordisk Foundation Center for Basic Metabolic Research Section for Metabolic Receptology and Enteroendocrinology Faculty of Health Sciences University of Copenhagen Copenhagen Denmark. New York University Langone Medical Center New York NY USA. Department of Microbiology Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA. RPU Immunobiology Department of Bacteriology & Immunology University of Helsinki Helsinki Finland. Laboratory of Microbiology Wageningen University Wageningen The Netherlands. Metagenopolis Institut National de la Recherche Agronomique Jouy en Josas France. King's College London Centre for Host-Microbiome Interactions Dental Institute Central Office Guy's Hospital London UK. Institute for Genome Sciences at the University of Maryland School of Medicine Baltimore MD USA. Graduate School of Advanced Science and Engineering Waseda University Tokyo Japan. Department of Biostatistics Harvard School of Public Health Boston MA USA. APC Microbiome Institute University College Cork Cork Ireland. Biotechnology Institute University of Minnesota Saint Paul MN USA. Department of Computer Science and Engineering University of Minnesota Minneapolis MN USA. Center for Clinical Epidemiology and Biostatistics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. MPI Department of Microbiome Science Tübingen Germany. Department of Integrative Biology University of Texas Austin TX USA. Warwick Medical School University

Population stratification is a useful approach for a better understanding of complex biological problems in human health and wellbeing. The proposal that such stratification applies to the human gut microbiome, in the form of distinct community composition types termed enterotypes, has been met with both excitement and controversy. In view of accumulated data and re-analyses since the original work, we revisit the concept of enterotypes, discuss different methods of dividing up the landscape of possible microbiome configurations, and put these concepts into functional, ecological and medical contexts. As enterotypes are of use in describing the gut microbial community landscape and may become relevant in clinical practice, we aim to reconcile differing views and encourage a balanced application of the concept.

关键词： Community composition landscapes

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A Multifunctional Controller Realized by Biochemical Reactions

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SICE Journal of Control, Measurement, and system Integration 2015年第2期8卷 99-107页

作者： Takashi Nakakuki Department of Systems Design and Informatics Faculty of Computer Science and Systems Engineering Kyushu Institute of Technology

A protein stabilization system is a type of post-transcriptional processing that ubiquitously exists in various types of cells, and it plays a major role in stabilizing the three-dimensional conformation of a translated protein. It comprises a series of activation-deactivation reactions coupled with nucleocytoplasmic shuttling, and it is described by a four-dimensional nonlinear ordinary differential equation based on chemical kinetics. This study shows that this system can variously function as two types of integral controllers, low-pass filter, and integrator depending on the combination of the statuses of cytoplasmic and nucleus enzymes that mediate its reaction rates. This indicates that the system is multifunctional, where these statuses are controlled by the peripheral system around the stabilization system. In particular, because realizing an integral controller for regulating the concentration of a particular molecule to a desired level in biochemical reactions is theoretically and technically important in molecular robotics, the author demonstrates some numerical simulation results regarding integral control.

关键词： biochemical reaction multifunctional system integral control molecular robotics

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Multiplicative noise effects on electroconvection in controlling additive noise by a magnetic field

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Physical Review E 2015年第6期92卷 062504-062504页

作者： Jong-Hoon Huh Department of Mechanical Information Science and Technology Faculty of Computer Science and Systems Engineering Kyushu Institute of Technology Fukuoka 820-8502 Japan

We report multiplicative noise-induced threshold shift of electroconvection (EC) in the presence of a magnetic field H. Controlling the thermal fluctuation (i.e., additive noise) of the rodlike molecules of nematic liquid crystals by H, the EC threshold is examined at various noise levels [characterized by their intensity and cutoff frequency (fc)]. For a sufficiently strong H (i.e., ignorable additive noise), a modified noise sensitivity characterizing the shift problem is in good agreement with experimental results for colored as well as white noise (fc→∞); until now, there was a large deviation for (sufficiently) colored noises. The present study shows that H provides us with ideal conditions for studying the corresponding Carr-Helfrich theory considering pure multiplicative noise.

关键词： ELECTROMAGNETIC noise RESEARCH CONVECTIVE flow (Fluid dynamics) MAGNETIC fields FLUCTUATIONS (Physics) WHITE noise

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROscience 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

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Nature genetics 2019年第7期51卷 1192-1193页

作者： Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany. Centre for Brain Research Indian Institute of Science Bangalore India. INSERM U1219 Bordeaux Population Health Research Center University of Bordeaux Bordeaux France. Stroke Research Group Division of Clinical Neurosciences University of Cambridge Cambridge UK. Department of Neurology Institute for Neurodegenerative Disease Bordeaux University Hospital Bordeaux France. Laboratory for Statistical Analysis RIKEN Center for Integrative Medical Sciences Yokohama Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Osaka Japan. Laboratory of Statistical Immunology Immunology Frontier Research Center (WPI-IFReC) Osaka University Suita Japan. Department of Neurology Massachusetts General Hospital (MGH) Harvard Medical School Boston MA USA. Laboratory of Experimental Cardiology Department of Cardiology Division of Heart and Lungs University Medical Center Utrecht University of Utrecht Utrecht the Netherlands. deCODE genetics/AMGEN Inc. Reykjavik Iceland. Center for Genomic Medicine MGH Boston MA USA. J. Philip Kistler Stroke Research Center Department of Neurology MGH Boston MA USA. Program in Medical and Population Genetics Broad Institute Cambridge MA USA. Population Health Research Institute McMaster University Hamilton Ontario Canada. Department of Epidemiology Erasmus University Medical Center Rotterdam the Netherlands. Department of Radiology and Nuclear Medicine Erasmus University Medical Center Rotterdam the Netherlands. Department of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan. Department of Clinical Sciences Lund University Malmö Sweden. INSERM Institut Pasteur de Lille LabEx DISTALZ-UMR1167 Risk Factors and Molecular Determinants of Aging-Related Diseases Université Lille Lille France. Centre Hospitalier Université Lille Epidemiology and Public Health D

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Mutation-based receiver search in a network for temporary information sharing

Mutation-based receiver search in a network for temporary in...

引用

Congress on Evolutionary Computation

作者： Kei Ohnishi Kazuya Tsukamoto Mario Köppen Gradate School of Computer Science and System Engineering Kyushu Institute of Technology Fukuoka Japan

This paper examines our previously proposed mutation-based search method for temporary information sharing in a wireless mesh network. The temporary information sharing indicates that for the case in which information senders and receivers freely appear in the network, information is forwarded from an information sender to a receiver. The mutation-based search method determines a unique route to find receivers who want the forwarded information by operations among numerical values assigned to each node and probabilistically changes the assigned numerical values according to the search results, which can be regarded as a sort of mutation in evolutionary computation. A variety of types of operations and numerical values can be used for this search method. In simulations, the method is evaluated in terms of search reliability under two appearance patterns of an information sender-receiver pair. One is the appearance pattern that locations of the receiver and the receiver are randomly determined. The other is that only a location of the receiver is fixed. Simulation results reveal that search reliability depends on the types of operations and numerical values and is related to how frequently a closed path is generated in the search. The results also suggest that the degree of randomness in search is important for reliable search and varies with the types of operations and numerical values.

关键词： Search methods Receivers Wireless communication Information management Relays Numerical models Concrete

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The status of KAGRA underground cryogenic gravitational wave telescope

arXiv

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arXiv 2017年

作者： Akutsu, T. Ando, M. Araya, A. Aritomi, N. Asada, H. Aso, Y. Atsuta, S. Awai, K. Barton, M.A. Cannon, K. Craig, K. Creus, W. Doi, K. Eda, K. Enomoto, Y. Flaminio, R. Fujii, Y. Fujimoto, M.-K. Furuhata, T. Haino, S. Hasegawa, K. Hashino, K. Hayama, K. Hirobayashi, S. Hirose, E. Hsieh, B.H. Inoue, Y. Ioka, K. Itoh, Y. Kaji, T. Kajita, T. Kakizaki, M. Kamiizumi, M. Kambara, S. Kanda, N. Kanemura, S. Kaneyama, M. Kang, G. Kasuya, J. Kataoka, Y. Kawai, N. Kawamura, S. Kim, C. Kim, H. Kim, J. Kim, Y. Kimura, N. Kinugawa, T. Kirii, S. Kitaoka, Y. Kojima, Y. Kokeyama, K. Komori, K. Kotake, K. Kumar, R. Lee, H. Lee, H. Liu, Y. Luca, N. Majorana, E. Mano, S. Marchio, M. Matsui, T. Matsushima, F. Michimura, Y. Miyakawa, O. Miyamoto, T. Miyamoto, A. Miyo, K. Miyoki, S. Morii, W. Morisaki, S. Moriwaki, Y. Morozumi, T. Musha, M. Nagano, S. Nagano, K. Nakamura, K. Nakamura, T. Nakano, H. Nakano, M. Nakao, K. Narikawa, T. Nguyen Quynh, L. Ni, W.-T. Ochi, T. Oh, J. Oh, S. Ohashi, M. Ohishi, N. Ohkawa, M. Okutomi, K. Oohara, K. Peña Alleano, F.E. Pinto, I. Sago, N. Saijo, M. Saito, Y. Sakai, K. Sakai, Y. Sasaki, Y. Sasaki, M. Sato, S. Sato, T. Sekiguchi, Y. Seto, N. Shibata, M. Shimoda, T. Shinkai, H. Shoda, A. Somiya, K. Son, E. Suemasa, A. Suzuki, T. Suzuki, T. Tagoshi, H. Takahashi, H. Takahashi, R. Takamori, A. Takeda, H. Tanaka, H. Tanaka, K. Tanaka, T. Tatsumi, D. Tomaru, T. Tomura, T. Travasso, F. Tsubono, K. Tsuchida, S. Uchikata, N. Uchiyama, T. Uehara, T. Ueki, S. Ueno, K. Ushiba, T. van Putten, M.H.P.M. Vocca, H. Wada, S. Wakamatsu, T. Yamada, T. Yamamoto, S. Yamamoto, T. Yamamoto, K. Yamamoto, A. Yokoyama, J. Yokozawa, T. Yoon, T.H. Yuzurihara, H. Zeidler, S. Zhu, Z.-H. National Astronomical Observatory of Japan Mitaka Tokyo181-8588 Japan Department of Physics University of Tokyo Bunkyo Tokyo113-0033 Japan Earthquake Research Institute University of Tokyo Bunkyo Tokyo113-0032 Japan Department of Advanced Physics Hirosaki University Hirosaki Aomori036-8561 Japan National Astronomical Observatory of Japan Hida Gifu506-1205 Japan Department of Physics Tokyo Institute of Technology Meguro Tokyo152-8551 Japan Institute for Cosmic Ray Research University of Tokyo Hida Gifu506-1205 Japan Research Center for the Early Universe University of Tokyo Bunkyo Tokyo113-0033 Japan Institute for Cosmic Ray Research University of Tokyo Kashiwa Chiba277-8582 Japan Institute of Physics Academia Sinica Nankang Taipei11529 Taiwan Department of Physics University of Toyama Toyama Toyama930-8555 Japan Faculty of Engineering University of Toyama Toyama Toyama930-8555 Japan Yukawa Institute for Theoretical Physics Kyoto University Sakyo Kyoto606-8502 Japan Department of Physics Osaka City University Sumiyosi Osaka558-8585 Japan Department of Physics Osaka University Toyonaka Osaka560-0043 Japan Korea Institute of Science and Technology Information Yuseong Daejeon34141 Korea Republic of Daejeon Yuseong34055 Korea Republic of National Institute for Mathematical Sciences Daejeon34047 Korea Republic of Department of Computer Simulation Inje University Gimhae Gyeongsangnam50834 Korea Republic of Department of Physics and Astronomy Seoul National University Seoul151-742 Korea Republic of High Energy Accelerator Research Organization Tsukuba Ibaraki305-0801 Japan Department of Physical Science Hiroshima University Higashihiroshima Hiroshima903-0213 Japan Department of Applied Physics Fukuoka University Jonan Fukuoka814-0180 Japan Department of Advanced Materials Science University of Tokyo Kashiwa Chiba277-8582 Japan Istituto Nazionale di Fisica Nucleare Sapienza University Roma00185 Italy D

KAGRA is a 3-km interferometric gravitational wave telescope located in the Kamioka mine in Japan. It is the first km-class gravitational wave telescope constructed underground to reduce seismic noise, and the first km-class telescope to use cryogenic cooling of test masses to reduce thermal noise. The construction of the infrastructure to house the interferometer in the tunnel, and the initial phase operation of the interferometer with a simple 3-km Michelson configuration have been completed. The first cryogenic operation is expected in 2018, and the observing runs with a full interferometer are expected in 2020s. The basic interferometer configuration and the current status of KAGRA are described. Copyright © 2017, The Authors. All rights reserved.

关键词： Interferometers

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Analysis and Visualization of Traffic Conditions of Road Network by Route Bus Probe Data

Analysis and Visualization of Traffic Conditions of Road Net...

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IEEE International Conference on Multimedia Big Data (BigMM)

作者： Dechen Liu Yusuke Kitamura Xin Zeng Shunsuke Araki Ken'fichi Kakizaki Faculty of Computer Science and Systems Engineering Kyushu Institute of Technology Fukuoka Japan

In recent years, route bus service systems have been collecting and accumulating bus probe data such as GPS positions and traffic speeds from all route buses, day after day. In the present paper, we propose a method to analyze the conditions of a road traffic network from a huge amount of the route bus probe data. First, we show a conversion method from the probe data to a road segment data set. Second, we introduce analysis methods that compute the degree of congestion and reachable areas from the road segment data set. Finally, we discuss road segment data structures for rapid calculations of these analytical methods.

关键词： Roads Probes Data mining Vehicles Global Positioning system Image color analysis Data visualization

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Application of facial reduction to H∞ state feedback control problem 8

Application of facial reduction to H∞ state feedback contro...

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8th IFAC Symposium on Robust Control Design, ROCOND 2015

作者： Waki, Hayato Sebe, Noboru Institute of Mathematics for Industry Kyushu University 744 Motooka Nishi-ku Fukuoka819-0395 Japan Department of Artificial Intelligence Faculty of Computer Science and Systems Engineering Kyushu Institute of Technology 680-4 Kawazu Iizuka-shi Fukuoka820-8502 Japan

One often encounters numerical difficulties in solving linear matrix inequality (LMI) problems obtained from H∞ control problems. We discuss the reason from the viewpoint of optimization. It is empirically known that a numerical difficulty occurs if the resulting LMI problem or its dual is not strongly feasible. In this paper, we provide necessary and sufficient conditions for LMI problem and its dual not to be strongly feasible, and interpret them in terms of control system. For this, facial reduction, which was proposed by Borwein and Wolkowicz, plays an important role. We show that a necessary and sufficient condition closely related to the existence of invariant zeros in the closed left-half plane in the system, and present a way to remove the numerical difficulty with the null vectors associated with invariant zeros in the closed left-half plane. Numerical results show that the numerical stability is improved by applying it. © 2015, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. All rights reserved.

关键词： Linear matrix inequalities

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Block based approach for key frame extraction on large video sequences

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ICIC Express Letters, Part B: Applications 2016年第12期7卷 2713-2717页

作者： Tin, Mie Mie Myo, Nyein Nyein Khin, Mie Mie Zin, Thi Thi Myanmar Institute of Information Technology P.O. Box 05053 73rd Street Ngu Shwe War Street Chanmyathazi Township Mandalay05053 Myanmar Information Science Department University of Computer Studies Mandalay Pathangyi Mandalay Myanmar Electrical and System Engineering Faculty of Engineering University of Miyazaki Kibana Campus 1-1 Gakuen Kibanadai-nishi Miyazaki-shi889-2192 Japan

Video segmentation and key frame extraction are very important in real world video systems. Key frames are essential to analyze on large amount of video frame sequences. This paper emphasizes surveillance video and the aim is to extract some meaningful key frames from long video sequences. This purpose is to reduce weak transaction frames in a large video stream by using block base algorithm and cluster the transition video shots. Kullback-Leible divergence method is used in key frame extraction for strong transition video shot. For weak transition video shot, the system will find three candidate key frames and they are compared. Key frames are meaningful frames for video sequences. These frames which represent video streams can be analyzed. Duplicated key frames from the video stream are analyzed in order to be extracted from different shots. Finally, key frames have many assets such as stability, accuracy, and summarize information for a large video. © 2016 ISSN 2185-2766.

关键词： Extraction

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