Emerging single-cell technologies profile different modalities of data in the same cell, providing opportunities to study cellular population and cell development at a res-olution that was previously inaccessible. The...
Emerging single-cell technologies profile different modalities of data in the same cell, providing opportunities to study cellular population and cell development at a res-olution that was previously inaccessible. The first and most fundamental step in analyzing single-cell multimodal data is the identification of the cell types in the data using clustering analysis and classification. However, combining different data modalities for the classification task in multimodal data remains a computational challenge. We propose an approach for identifying cell types in multimodal omics data via joint dimensionality reduction. We first introduce a general framework that extends loss based dimensionality reduction methods such as nonnegative matrix factorization and UMAP to multimodal omics data. Our approach can learn the relative contribution of each modality to a concise representation of cellular identity that enhances discriminative features and decreases the effect of noisy features. The precise representation of the multimodal data in a low dimensional space improves the predictivity of classification methods. In our experiments using both synthetic and real data, we show that our framework produces unified embeddings that agree with known cell types and allows the predictive algorithms to annotate the cell types more accurately than state-of-the-art classification methods.
Implicit neural representations (INRs) have gained prominence as a powerful paradigm in scene reconstruction and computer graphics, demonstrating remarkable results. By utilizing neural networks to parameterize data t...
Implicit neural representations (INRs) have gained prominence as a powerful paradigm in scene reconstruction and computer graphics, demonstrating remarkable results. By utilizing neural networks to parameterize data through implicit continuous functions, INRs offer several benefits. Recognizing the potential of INRs beyond these domains, this survey aims to provide a comprehensive overview of INR models in the field of medical imaging. In medical settings, numerous challenging and ill-posed problems exist, making INRs an attractive solution. The survey explores the application of INRs in various medical imaging tasks, such as image reconstruction, segmentation, registration, novel view synthesis, and compression. It discusses the advantages and limitations of INRs, highlighting their resolution-agnostic nature, memory efficiency, ability to avoid locality biases, and differentiability, enabling adaptation to different tasks. Furthermore, the survey addresses the challenges and considerations specific to medical imaging data, such as data availability, computational complexity, and dynamic clinical scene analysis. It also identifies future research directions and opportunities, including integration with multi-modal imaging, real-time and interactive systems, and domain adaptation for clinical decision support. To facilitate further exploration and implementation of INRs in medical image analysis, we have provided a compilation of cited studies along with their available open-source implementations on ${\color{Magenta}GitHub}$. Finally, we aim to consistently incorporate the most recent and relevant papers regularly.
DNA Barcodes, which are particular fragments derived from brief sections of DNA (such as mitochondrial, nuclear, and plastid sequences), can be used to identify organisms from the major life kingdoms. In addition to s...
DNA Barcodes, which are particular fragments derived from brief sections of DNA (such as mitochondrial, nuclear, and plastid sequences), can be used to identify organisms from the major life kingdoms. In addition to supporting conventional taxonomic techniques, DNA barcoding is a potent tool that advances our knowledge of species diversity and their ecological functions. On a variety of organisms, the use of this approach for species categorization has been successful. In this paper, we examine how DNA barcoding has been used to classify species based on DNA barcodes as well as other related research that has been done over the years on the subject. After experimenting with a number of deep learning models, we have propose a Variational Auto Encoder + Feed Forward Neural Network workflow for classifiying species using DNA barcodes. The models have been assessed on the basis of performance factors including accuracy, recall, and precision. COI, rbcL, matK, and ITS are the specific gene sections that have been identified as barcodes. For both simulated and real datasets, the model can attain an average accuracy of greater than 95 percent. This DNA barcoding approach has the ability to simplify DNA barcode-based species identification and serve as a tool for species categorization.
Over recent years, designers have encountered several challenges on how to capture and analyze human factors needed for effective design of interactive systems. In most cases, much effort is kept on functional require...
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This is the era of I-way. The development of high-speed computing and huge storage devices change the working culture of human. It affects the traditional business processes and shifted towards online business. It cre...
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The article the efficiency of the Microgrid network when transitioning to a transactive power system that uses control algorithms called to optimize the distribution of power between sources of distributed generation ...
The article the efficiency of the Microgrid network when transitioning to a transactive power system that uses control algorithms called to optimize the distribution of power between sources of distributed generation and to minimize the time of decision-making about mode switching and at the corresponding change of the power system architecture. Tables and graphs of the conducted modeling are presented and the efficiency of this control-optimized system is calculated in comparison with the power system where uniform distribution of load power is used.
Association rule mining has been an important approach for feature and biomarker discovery in various omics data. One main challenge is that it generates a large number of itemsets. The effect of this shortcoming incr...
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The main factor for plant growth is fertilization. Fertilization is one of the important processes in plant growth that aims to add nutrients that are completely absorbed by plants. But excessive fertilization can dam...
The main factor for plant growth is fertilization. Fertilization is one of the important processes in plant growth that aims to add nutrients that are completely absorbed by plants. But excessive fertilization can damage the soil structure as well as plants become vulnerable to pests and wasting costs. However, until now, many farmers still apply fertilizer without knowing for sure the nutrient content of the soil; Meanwhile, checking the nutritional content of plants uses chemical solutions and sensors which are relatively expensive, making it difficult for farmers to implement. Based on this problem, this research aims to propose a new approach in the accuracy of fertilization based on soil pH sensors., by utilizing Internet of Things technology, this research focuses on providing recommendations for IoT-based fertilizers using soil pH sensors, the results of the sensors will be correlated with nutrients contained in the soil. Prediction of soil nutrient content is obtained from the correlation between plant environmental conditions. With this system, farmers can monitor the soil density around the plant and get fertilization recommendations through smartphones, and will get notifications of dosage recommendations and types of fertilizers if the pH condition is beyond the normal limit that has been determined. Based on the trials that have been carried out, the system can run well.
This study addresses the burgeoning demand for website data collection and analysis in business operations, emphasizing the pivotal role of web analytics in providing crucial insights into customer behaviour. Despite ...
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The assessment of Alzheimer’s Disease (AD) progression via the analysis of physical changes within the brain has attracted great interest from the fields of healthcare, computational medicine, and machine learning al...
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ISBN:
(数字)9781665468190
ISBN:
(纸本)9781665468206
The assessment of Alzheimer’s Disease (AD) progression via the analysis of physical changes within the brain has attracted great interest from the fields of healthcare, computational medicine, and machine learning alike. Recent studies have demonstrated that using both multi-modal data and multiple AD assessment scores in a predictive model can better reflect pathological characteristics and enhance prediction performance. However, using such high-dimensional structure information to model inter-correlation between multiple targets remains a challenging task. In this paper, we propose a Tensor-based Multi-modal Multi-Target Regression (TMMTR) method for AD detection and prediction, which enables simultaneously modeling multilinear structure information as well as intrinsic inter-target correlations in a general learning framework. We also investigate the tensor-structured sparsity that supports the interpretability of our prediction. Experiments conducted on the ADNI dataset validate the superior performance of our method when compared to other state-of-the-art methods.
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